WORK PACKAGE 1
LEADER: LCPO, Université de Bordeaux, France
Design of smart nanocapsules with enzyme and/or pH triggered release of hydrophobic or hydrophilic actives
This WP will be dedicated to the optimization of the emulsifier HLB to stabilize either hydrophilic or lipophilic active ingredients. The assembled nanocapsules will be selected in terms of their size, stability and ability to release the actives.
WORK PACKAGE 2
LEADER: POLYMAT, Universidad del País Vasco/Euskal Herriko Unibertsitatea, Spain
Production of smart nanocapsules using industrially-relevant manufacturing processes under cosmetic GMP
This WP will be dedicated to the production of nanocapsules with industrially relevant processes, namely High Pressure Homogenizer and Tubular flow membrane contactor, according to the Cosmetic Good Manufacturing Practice (ISO 22716).
WORK PACKAGE 3
LEADER: AHAVA Dead Sea Laboratories LTD, Israel
Validation of smart nanocapsules in relevant skin conditions
This WP will focus on the validation of the action of the nanocapsules for the skin conditions considered in PeptiCaps using validated skin models. Those results will be gathered to put together the “Dossier” required for the validation of the nanocapsules as new cosmetic ingredients.
WORK PACKAGE 4
LEADER: Istituto di Ricerche Farmacologiche Mario Negri, Italy
Risk and safety assessment of smart nanocapsules. Software to predict risk and safety of nanomaterials
The tasks of this WP will be dedicated to the study of the toxicity and ecotoxicity of the nanocapsules to ensure its safe used for future commercialization. Those analysis will be included in the Dossier for the validation of the nanocapsules as safe cosmetic ingredient. In addition, computer software will be developed to predict the safety of nanomaterials.
WORK PACKAGE 5
LEADER: SPINVERSE, Finland
Business and Dissemination Plan
This important WP will aim at first advertising the projects and its outcome via conference or publication to the scientific community as well as industries and general public.
In addition, a business analysis and strategy to commercialize PeptiCaps nanocapsules will be established. Plans for exploitation of the outcomes, including IPR-strategy, will be established to finally deliver a business plan.
WORK PACKAGE 6
LEADER: IK4-CIDETEC, Spain
Project Management and Scientific Coordination
WP6 will guarantee optimal administrative, financial, contractual as well as scientific consortium management. One important task of this WP for the success of the project will be to ensure efficient communication and fruitful collaboration between the partners.